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S DS, et al.: Role of surfactant protein-A (SP-A) in lung injury in response to acute ozone exposure of SP-A deficient mice. Toxicol Appl Pharmacol 2007, 220:72-82. 32. Korfhagen TR, LeVine AM, Whitsett JA: Surfactant protein A (SP-A) gene targeted mice. Biochim Biophys Acta 1998, 1408:296-302. 33. LeVine AM, Hartshorn K, Elliott J, Whitsett J, Korfhagen T: Absence of SP-A modulates innate and ada
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Ologs. The second objective of the study was to examine the genome wide transcriptional responses to xenobiotic compounds using whole genome tiling arrays recently made available in Oikopleura. Oikopleura was exposed to two model xenobiotic compounds benzo[a]pyrene (BaP) and clofibrate (Clo) that are common environmental pollutants. BaP is a carcinogenic polycyclic aromatic hydrocarbon (PAH) that
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Imilar topology (Additional file 1, Figure S1). See Additional file 2 for the full list of O. dioica CYP proteins and their accessions. O. dioica (Od) sequences are shown in blue.Yadetie et al. BMC Genomics 2012, 13:55 http://www.biomedcentral.com/1471-2164/13/Page 4 ofCYP3-like-2 (CBY21750) and CYP2-like-11 (CBY24358) genes, respectively (Additional files 3 and 4).Lack of detection of AhR signali
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Imized formulations . Currently, several VLP-based vaccine candidates for human diseases areImized formulations . Currently, several VLP-based vaccine candidates for human diseases are under clinical development including those directed against Influenza A virus, Norwalk virus, Ebola and Marburg viruses, Hepatitis C virus, HIV and Malaria. To date, VLP-based vaccines for human papilloma viru
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S DS, et al.: Role of surfactant protein-A (SP-A) in lung injury in response to acute ozone exposure of SP-A deficient mice. Toxicol Appl Pharmacol 2007, 220:72-82. 32. Korfhagen TR, LeVine AM, Whitsett JA: Surfactant protein A (SP-A) gene targeted mice. Biochim Biophys Acta 1998, 1408:296-302. 33. LeVine AM, Hartshorn K, Elliott J, Whitsett J, Korfhagen T: Absence of SP-A modulates innate and ada
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Ompared to WT mice [12,15], suggesting that, at least with respect to K. pneumoniae, direct effects of SPA on host defense function (i.e. enhancement of phagocytosis) are more important than the pleiotropic indirect effects on the BAL proteome.8. 9.10.Additional materialAdditional file 1 MIAPE: Gel Electrophoresis. File containing Minimum information about a proteomics experiment - Gel Electrophor
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N the BAL proteome after Klebsiella pneumoniae infection in wild type and SP-A-/- mice Proteome Science 2010, 8:Staphylococcus aureus is a commensal of humans that permanently colonises the anterior nares of about 20 of the population with the remainder being colonised transiently [1]. The bacterium is an opportunistic pathogen that can cause a variety of disorders ranging in severity from
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Luid. Vet Immunol Immunopathol 2008, 125:111-125. Bowler RP, Reisdorph N, Reisdorph R, Abraham E: Alterations in the human lung proteome with lipopolysaccharide. BMC Pulm Med 2009, 9:20. Umstead TM, Freeman WM, Chinchilli VM, Phelps DS: Age-related changes in the expression and oxidation of bronchoalveolar lavage proteins in the rat. Am J Physiol Lung Cell Mol Physiol 2009, 296:L14-L29.Ali et al.

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