Implicating an Epac role inside the development and upkeep of the anxious program (Christensen et al., 2003; Kiermayer et al., 2005; Shi et al., 2006; Murray and Shewan, 2008). Moreover and maybe applicable towards the ICH-pathology, Epac proteins have already been implicated in vascular functionality. In vivo administration of a Epac agonist (007) inhibited vascular endothelial development factor
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